Le'boins will be constantly spawned. They appear as a main threat.
For all chapters - As always, start upgrading your Cat Wallet to max level, when enemies will come close to your base, send out few Tank Cats/Wall Cats. When Jackie Peng will be approaching your base, send out Bird Cats/Ufo Cats and meatshields. Altrough, when Gory comes send out Titan Cat/Mythical Titan Cat, Gross Cats/Sexy Legs Cats. And don't forget about Fish Cat/Whale Cat .That cat will help you against Sir Seal. After short time, Le'boin will be spawned. That's when things become serious. You will need to spam Titan Cats/Mythical Titan Cats along with Gross Cats/Sexy Legs Cats, Lizard Cats/Dragon Cats and meatshields. If you won't be fast enough, another Le'boin will spawn.